Detalhe da pesquisa
1.
Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma.
Mol Cell
; 84(4): 776-790.e5, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38211588
2.
Genome-wide Screening Identifies SFMBT1 as an Oncogenic Driver in Cancer with VHL Loss.
Mol Cell
; 77(6): 1294-1306.e5, 2020 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32023483
3.
Noncanonical HPV carcinogenesis drives radiosensitization of head and neck tumors.
Proc Natl Acad Sci U S A
; 120(32): e2216532120, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37523561
4.
USP13 promotes deubiquitination of ZHX2 and tumorigenesis in kidney cancer.
Proc Natl Acad Sci U S A
; 119(36): e2119854119, 2022 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36037364
5.
Enabling Genetic Code Expansion and Peptide Macrocyclization in mRNA Display via a Promiscuous Orthogonal Aminoacyl-tRNA Synthetase.
J Am Chem Soc
; 145(3): 1512-1517, 2023 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36630539
6.
Insight into Viral Hijacking of CRL4 Ubiquitin Ligase through Structural Analysis of the pUL145-DDB1 Complex.
J Virol
; 96(17): e0082622, 2022 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35938868
7.
USP37 promotes deubiquitination of HIF2α in kidney cancer.
Proc Natl Acad Sci U S A
; 117(23): 13023-13032, 2020 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32461361
8.
p85α SH2 domain phosphorylation by IKK promotes feedback inhibition of PI3K and Akt in response to cellular starvation.
Mol Cell
; 45(6): 719-30, 2012 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22342344
9.
Thioridazine inhibits self-renewal in breast cancer cells via DRD2-dependent STAT3 inhibition, but induces a G1 arrest independent of DRD2.
J Biol Chem
; 293(41): 15977-15990, 2018 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30131338
10.
Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli.
Immunity
; 33(1): 35-47, 2010 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20643337
11.
Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity.
J Biol Chem
; 292(13): 5405-5417, 2017 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28188292
12.
Targeting the Canonical Nuclear Factor-κB Pathway with a High-Potency IKK2 Inhibitor Improves Outcomes in a Mouse Model of Idiopathic Pneumonia Syndrome.
Biol Blood Marrow Transplant
; 23(4): 569-580, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28161607
13.
Regulation of cell death and autophagy by IKK and NF-κB: critical mechanisms in immune function and cancer.
Immunol Rev
; 246(1): 327-45, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22435564
14.
Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).
J Biol Chem
; 289(36): 25227-40, 2014 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24990947
15.
Altered T-cell entry and egress in the absence of Coronin 1A attenuates murine acute graft versus host disease.
Eur J Immunol
; 44(6): 1662-71, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24752751
16.
Deletion of the NF-κB subunit p65/RelA in the hematopoietic compartment leads to defects in hematopoietic stem cell function.
Blood
; 121(25): 5015-24, 2013 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23670180
17.
LZAP, a putative tumor suppressor, selectively inhibits NF-kappaB.
Cancer Cell
; 12(3): 239-51, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17785205
18.
B cells from patients with chronic GVHD are activated and primed for survival via BAFF-mediated pathways.
Blood
; 120(12): 2529-36, 2012 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22896003
19.
Dihydroartemisinin ameliorates inflammatory disease by its reciprocal effects on Th and regulatory T cell function via modulating the mammalian target of rapamycin pathway.
J Immunol
; 189(9): 4417-25, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22993204
20.
Using NMR to Monitor TET-Dependent Methylcytosine Dioxygenase Activity and Regulation.
ACS Chem Biol
; 19(1): 15-21, 2024 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38193366